Dr. Luke Findley is on the midnight shift in the emergency room when the police bring in a young woman. Few strangers come to this remote town in northernmost Maine in the winter, and this stranger is accused of a bizarre crime: killing a man and leaving his body in the Great North Woods. The young woman, Lanny, tells the doctor that she and the man in the woods lived in this town at its founding two hundred years ago, until fate sentenced them to an eternity of unhappiness until they atone for their sins.
The man in the woods is Jonathan, son of the town's founder, and the love of Lanny's life. After Lanny commits a terrible sin in the hope of claiming Jonathan for her own, she's banished from town and sent to Boston to serve her penance. In Boston, she falls in with a beguiling yet frightening man, Adair, who has otherworldly powers, including the ability to confer immortality. His world is one of unknown sensual pleasures and seemingly limitless power, but at what price?